CD3 anticorps (AbBy Fluor® 350)

N° du produit ABIN7090892

Cet anticorps anti-CD3 est un anticorps Souris Monoclonal détectant CD3 dans FACS. Adapté pour Humain.

Aperçu rapide pour CD3 anticorps (AbBy Fluor® 350) (ABIN7090892)

Antigène: CD3

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD3 est conjugé à/à la AbBy Fluor® 350

Application: Flow Cytometry (FACS)

Clone: HIT3b

Détail du produit anti-CD3 anticorps (AbBy Fluor® 350)

Réactivité croisée: Humain

Purification: Purified by Protein G.

Immunogène: KLH conjugated synthetic peptide derived from human CD3

Isotype: IgG1

Information d'application

Indications d'application: FCM 1:20-100

Restrictions: For Research Use only

Stockage

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Détails sur CD3

Antigène: CD3

Autre désignation: CD3

Sujet:

Synonyms: CD3e Molecule, CD3e Antigen, Epsilon Polypeptide (TiT3 Complex), T-Cell Surface Antigen T3/Leu-4 Epsilon Chain, CD3e Molecule, Epsilon (CD3-TCR Complex), T3E, T-Cell Antigen Receptor Complex, Epsilon Subunit Of T3, T-Cell Surface Glycoprotein CD3 Epsilon Chain, CD3e Antigen, CD3-Epsilon, IMD18, TCRE,

Background: The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. [provided by RefSeq, Jul 2008].

ID gène: 12501

UniProt: P22646

Pathways: TCR Signaling, Ubiquitin Proteasome Pathway