F2RL3 anticorps (AA 101-200)

N° du produit ABIN7090992

Cet anticorps Lapin Polyclonal détecte spécifiquement F2RL3 dans WB et ELISA. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour F2RL3 anticorps (AA 101-200) (ABIN7090992)

Antigène: F2RL3 (Coagulation Factor II (Thrombin) Receptor-Like 3 (F2RL3))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp F2RL3 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-F2RL3 anticorps

Épitope: AA 101-200

Réactivité croisée: Humain, Souris, Rat

Homologie: Cow,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human PAWR

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000

Restrictions: For Research Use only

Stockage

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur F2RL3

Antigène: F2RL3 (Coagulation Factor II (Thrombin) Receptor-Like 3 (F2RL3))

Autre désignation: Par-4

Sujet:

Synonyms: 2310001G03Rik , PAR 4 , PAR-4 , Pawr , PAWR_HUMAN , PRKC Apoptosis WT1 Regulator , PRKC apoptosis WT1 regulator protein , Prostate apoptosis response 4 protein , Prostate apoptosis response protein 4 , prostate apoptosis response protein PAR-4 , Transcriptional repressor Par-4-like protein PAWR , Transcriptional repressor PAR4 , WT1 Interacting Protein

Background: Pro-apoptopic protein capable of selectively inducing apoptosis in cancer cells, sensitizing the cells to diverse apoptotic stimuli and causing regression of tumors in animal models. Induces apoptosis in certain cancer cells by activation of the Fas prodeath pathway and coparallel inhibition of NF-kappa-B transcriptional activity. Inhibits the transcriptional activation and augments the transcriptional repression mediated by WT1. Down-regulates the anti-apoptotic protein BCL2 via its interaction with WT1. Seems also to be a transcriptional repressor by itself. May be directly involved in regulating the amyloid precursor protein (APP) cleavage activity of BACE1.

ID gène: 5074

UniProt: Q96IZ0

Pathways: Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process