DKK2 anticorps

N° du produit ABIN7091038

L’anticorps anti-DKK2 Monoclonal produit chez le Souris a été validé pour WB. Il convient pour la détection de DKK2 dans des échantillons provenant de Humain. }

Aperçu rapide pour DKK2 anticorps (ABIN7091038)

Antigène: DKK2 (Dickkopf 2 Homolog (DKK2))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp DKK2 est non-conjugé

Application: Western Blotting (WB)

Clone: J3F5

Détail du produit anti-DKK2 anticorps

Homologie: Human,Mouse

Immunogène: Recombinant human DKK2.

Information d'application

Indications d'application: WB 1:300-5000

Restrictions: For Research Use only

Stockage

Concentration: 0.5 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur DKK2

Antigène: DKK2 (Dickkopf 2 Homolog (DKK2))

Autre désignation: DKK2

Sujet:

Synonyms: Dickkopf 2, Dickkopf gene 2, Dickkopf homolog 2, Dickkopf related protein 2, Dickkopf-2, Dickkopf-related protein 2, Dickkopf2, DKK 2, Dkk-2, DKK2_HUMAN, hDkk 2, hDkk-2, hDkk2.

Background: Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease.

ID gène: 27123

UniProt: Q9UBU2

Pathways: Signalisation WNT