Growth Hormone Receptor anticorps (AA 551-638) (Biotin)

N° du produit ABIN7091180

Cet anticorps anti-Growth Hormone Receptor est un anticorps Lapin Polyclonal détectant Growth Hormone Receptor dans WB et ELISA. Adapté pour Humain.

Aperçu rapide pour Growth Hormone Receptor anticorps (AA 551-638) (Biotin) (ABIN7091180)

Antigène: Growth Hormone Receptor (GHR)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Growth Hormone Receptor est conjugé à/à la Biotin

Application: Western Blotting (WB), ELISA

Détail du produit anti-Growth Hormone Receptor anticorps (Biotin)

Épitope: AA 551-638

Réactivité croisée: Humain

Homologie: Dog,Cow,Sheep,Pig,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human GHR

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000

Restrictions: For Research Use only

Stockage

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur Growth Hormone Receptor

Antigène: Growth Hormone Receptor (GHR)

Autre désignation: Growth hormone receptor

Sujet:

Synonyms: GH receptor, GHBP, GHR, Growth hormone receptor precursor, Serum binding protein, Somatotropin receptor, GHR_HUMAN.

Background: Receptor for pituitary gland growth hormone involved in regulating postnatal body growth. On ligand binding, couples to the JAK2/STAT5 pathway.
The soluble form (GHBP) acts as a reservoir of growth hormone in plasma and may be a modulator/inhibitor of GH signaling.
Isoform 2 up-regulates the production of GHBP and acts as a negative inhibitor of GH signaling.

ID gène: 2690

UniProt: P10912

Pathways: Signalisation NF-kappaB, Signalistation JAK/STAT, Response to Growth Hormone Stimulus