ITGAL anticorps

N° du produit ABIN7091261

Cet anticorps anti-ITGAL est un anticorps Souris Monoclonal détectant ITGAL dans IF et ICC. Adapté pour Humain.

Aperçu rapide pour ITGAL anticorps (ABIN7091261)

Antigène: ITGAL (Integrin alpha-L (ITGAL))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp ITGAL est non-conjugé

Application: Immunofluorescence (IF), Immunocytochemistry (ICC)

Clone: A13C2

Détail du produit anti-ITGAL anticorps

Homologie: Human

Purification: Purified by Protein G.

Immunogène: KLH conjugated synthetic peptide derived from human CD11a

Isotype: IgG

Information d'application

Indications d'application: IF()
ICC 1:100-500

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur ITGAL

Antigène: ITGAL (Integrin alpha-L (ITGAL))

Autre désignation: CD11a

Sujet:

Synonyms: CD11a, Integrin alpha-L, Leukocyte adhesion glycoprotein LFA-1 alpha chain, LFA-1A, Leukocyte function-associated molecule 1 alpha chain, Lymphocyte antigen 15, Ly-15, CD11 antigen-like family member A, CD_antigen, ITAL_HUMAN.

Background: ITGAL encodes the integrin alpha L chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form the integrin lymphocyte function-associated antigen-1 (LFA-1), which is expressed on all leukocytes. LFA-1 plays a central role in leukocyte intercellular adhesion through interactions with its ligands, ICAMs 1-3(intercellular adhesion molecules 1 through 3), and also functions in lymphocyte costimulatory signaling. Two transcript variants encoding different isoforms have been found for this gene.

ID gène: 3683

UniProt: P20701

Pathways: Activated T Cell Proliferation, Integrin Complex