Patched 1 anticorps (AA 1-100) (Biotin)

N° du produit ABIN7091515

L’anticorps Lapin Polyclonal anti-Patched 1 a été validé pour WB et ELISA. Il convient pour détecter Patched 1 dans des échantillons de Souris et Rat.

Aperçu rapide pour Patched 1 anticorps (AA 1-100) (Biotin) (ABIN7091515)

Antigène: Patched 1 (PTCH1)

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Patched 1 est conjugé à/à la Biotin

Application: Western Blotting (WB), ELISA

Détail du produit anti-Patched 1 anticorps (Biotin)

Épitope: AA 1-100

Réactivité croisée: Souris, Rat

Homologie: Human,Pig

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human Patched

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000

Restrictions: For Research Use only

Stockage

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur Patched 1

Antigène: Patched 1 (PTCH1)

Autre désignation: Patched

Sujet:

Synonyms: Protein patched homolog 1, PTCH, PTC1, A230106A15Rik, BCNS, FLJ26746, FLJ42602, Holoprosencephaly 7, HPE7, mes, NBCCS, OTTHUMP00000021709, OTTHUMP00000021710, Patched, Patched (Drosophila) homolog, Patched 1, Patched homolog (Drosophila), Patched homolog 1 (Drosophila), Patched homolog 1, Patched protein homolog 1, PTC, PTC1, PTCH, PTCH protein +12b, PTCH protein +4', PTCH protein -10, PTCH protein, PTCH1, PTCH1 protein, PTCH11, Ptch2, , Patched / PTCH, PTC1_HUMAN.

Background: Acts as a receptor for sonic hedgehog (SHH), indian hedgehog (IHH) and desert hedgehog (DHH). Associates with the smoothened protein (SMO) to transduce the hedgehog's proteins signal. Seems to have a tumor suppressor function, as inactivation of this protein is probably a necessary, if not sufficient step for tumorigenesis.

ID gène: 5727

UniProt: Q13635

Pathways: Signalisation Hedgehog, Carbohydrate Homeostasis, Tube Formation