Girdin anticorps (pSer1765)

N° du produit ABIN7091890

Détail du produit anti-Girdin anticorps

Antigène: Girdin (CCDC88A) (Coiled-Coil Domain Containing 88A (CCDC88A))

Épitope: pSer1765

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp Girdin est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Homologie: Human,Mouse,Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthesised phosphopeptide derived from human APE around the phosphorylation site of Ser1765

Clone: G5F7

Isotype: IgG

Information d'application

Indications d'application: IHC-P 1:200-400

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur Girdin

Antigène: Girdin (CCDC88A) (Coiled-Coil Domain Containing 88A (CCDC88A))

Autre désignation: Girdin (CCDC88A Produits)

Synonymes: anticorps APE, anticorps GIRDIN, anticorps GIV, anticorps GRDN, anticorps HkRP1, anticorps KIAA1212, anticorps A430106J12Rik, anticorps AI848406, anticorps Ape, anticorps C130096N06Rik, anticorps C330012F17Rik, anticorps D130005J21Rik, anticorps Girdin, anticorps Giv, anticorps Grdn, anticorps Hkrp1, anticorps DKFZp459N1815, anticorps RGD1306694, anticorps coiled-coil domain containing 88A, anticorps coiled coil domain containing 88A, anticorps CCDC88A, anticorps Ccdc88a

Sujet:

Synonyms: GIV (pY1765), Girdin (phospho Y1765), p-Girdin (phospho Y1765), Akt phosphorylation enhancer, APE, Coiled coil domain containing protein 88A, G alpha interacting vesicle associated protein, Girders of actin filament, GIV, HkRP1, Hook related protein 1, AKT iphosphorylation enhancer, Akt phosphorylation enhancer, Ccdc88a, GIV, GRDN, GRDN_HUMAN, HkRP1, Hook related protein 1, Hook-related protein 1, KIAA1212.

Background: This gene encodes a member of the Girdin family of coiled-coil domain containing proteins. The encoded protein is an actin-binding protein that is activated by the serine/threonine kinase Akt and plays a role in cytoskeleton remodeling and cell migration. The encoded protein also enhances Akt signaling by mediating phosphoinositide 3-kinase (PI3K)-dependent activation of Akt by growth factor receptor tyrosine kinases and G protein-coupled receptors. Increased expression of this gene and phosphorylation of the encoded protein may play a role in cancer metastasis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]

ID gène: 55704

UniProt: Q3V6T2