CD86 anticorps (AA 26-247)

N° du produit ABIN7092885

Cet anticorps Lapin Monoclonal détecte spécifiquement CD86 dans FACS et ELISA. Il présente une réactivité envers Humain.

Aperçu rapide pour CD86 anticorps (AA 26-247) (ABIN7092885)

Antigène: CD86

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp CD86 est non-conjugé

Application: Flow Cytometry (FACS), ELISA

Clone: DM84

Détail du produit anti-CD86 anticorps

Épitope: AA 26-247

Purification: Purified from cell culture supernatant by affinity chromatography

Immunogène: Recombinant human B7-2 (Leu26-Pro247) (ABIN6961107) produced by using human HEK293 cells

Isotype: IgG

Information d'application

Indications d'application: ELISA 1/5000-10000,Flow Cyt  1/100

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Reconstitute with deionized water

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.,0.1 % Procline 300

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Date de péremption: 12 months

Détails sur CD86

Antigène: CD86

Autre désignation: B7-2

Sujet: Synonyms:CD86, B7-2, B70, CD28LG2, LAB72, MGC34413
Description:This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.

Poids moléculaire: 37.7kDa

ID gène: 942

UniProt: P42081

Pathways: TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation