Mesothelin anticorps (AA 296-580) (Biotin)

N° du produit ABIN7093016

Cet anticorps anti-Mesothelin Monoclonal Lapin conjugué à Biotin (Clone DM71) (ABIN7093016) détecte spécifiquement Mesothelin dans ELISA et FACS. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour Mesothelin anticorps (AA 296-580) (Biotin) (ABIN7093016)

Antigène: Mesothelin (MSLN)

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp Mesothelin est conjugé à/à la Biotin

Application: ELISA, Flow Cytometry (FACS)

Clone: DM71

Détail du produit anti-Mesothelin anticorps (Biotin)

Épitope: AA 296-580

Fonction: Biotinylated Anti-mesothelin antibody(DM71), Rabbit mAb

Purification: Purified from cell culture supernatant by affinity chromatography

Immunogène: Recombinant human mesothelin (Glu296-Gly580) (ABIN6961104) produced by using human HEK293 cells

Isotype: IgG

Information d'application

Indications d'application: ELISA 1:5000-10000, Flow Cyt 1:100

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Please see Certificate of Analysis for specific instructions of reconstitution.

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Stock: -20 °C,-80 °C

Stockage commentaire: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Date de péremption: 12 months

Détails sur Mesothelin

Antigène: Mesothelin (MSLN)

Autre désignation: MSLN

Sujet: Synonyms:MSLN, Mesothelin, MPF
Description:This gene encodes a preproprotein that is proteolytically processed to generate two protein products, megakaryocyte potentiating factor and mesothelin. Megakaryocyte potentiating factor functions as a cytokine that can stimulate colony formation of bone marrow megakaryocytes. Mesothelin is a glycosylphosphatidylinositol-anchored cell-surface protein that may function as a cell adhesion protein. This protein is overexpressed in epithelial mesotheliomas, ovarian cancers and in specific squamous cell carcinomas. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.

Poids moléculaire: 68.9kDa

ID gène: 10232

UniProt: Q13421

Pathways: EGFR Signaling Pathway, Positive Regulation of Peptide Hormone Secretion, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Carbohydrate Homeostasis, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process