ACO2 anticorps (AA 51-246)

N° du produit ABIN7111197

Cet anticorps anti-ACO2 est un anticorps Lapin Polyclonal détectant ACO2 dans WB, ELISA, IHC et IF. Adapté pour Humain, Rat et Souris.

Aperçu rapide pour ACO2 anticorps (AA 51-246) (ABIN7111197)

Antigène: ACO2 (Aconitase 2, Mitochondrial (ACO2))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ACO2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-ACO2 anticorps

Épitope: AA 51-246

Fonction: ACO2 antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène:

Immunogen sequence: 51-246aa

Immunogen: aconitase 2, mitochondrial

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:2000, IHC: 1:20-1:200, IF: 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur ACO2

Antigène: ACO2 (Aconitase 2, Mitochondrial (ACO2))

Autre désignation: ACO2

Sujet:

Synonyms: Aconitate hydratase, mitochondrial (Aconitase)|Citrate hydro-lyase|ACO2

Background: ACO2(aconitate hydratase, mitochondrial) is also named as citrate hydro-lyase and belongs to the aconitase/IPM isomerase family. It plays a key function in cellular energy production, and loss of its activity has a major impact on cellular and organismal survival. Western blot shows two bands of 83 kDa and 40 kDa. The 40 kDa fragment decreases with age and oxidative stress, whereas other fragmentation products with molecular weights between 40 and 83 kDa increased with age and MnSOD(mitochondrial manganese superoxide dismutase) deficiency(PMID:12459471). Defects in ACO2 are the cause of infantile cerebellar-retinal degeneration(ICRD).

Poids moléculaire: 85 kDa

ID gène: 50

UniProt: Q99798