ATF6B anticorps

N° du produit ABIN7111248

Cet anticorps anti-ATF6B est un anticorps Lapin Polyclonal détectant ATF6B dans WB, ELISA, IHC, IF et IP. Adapté pour Humain, Souris et Rat.

Aperçu rapide pour ATF6B anticorps (ABIN7111248)

Antigène: ATF6B (Activating Transcription Factor 6 beta (ATF6B))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ATF6B est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)

Détail du produit anti-ATF6B anticorps

Fonction: ATF6B antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: activating transcription factor 6 beta

Isotype: IgG

Information d'application

Indications d'application: WB: 1:1000-1:4000, IP:1:500-1:2000, IHC: 1:20-1:200, IF: 1:10-1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur ATF6B

Antigène: ATF6B (Activating Transcription Factor 6 beta (ATF6B))

Autre désignation: ATF6B

Sujet:

Synonyms: Cyclic AMP-dependent transcription factor ATF-6 beta (cAMP-dependent transcription factor ATF-6 beta)|Activating transcription factor 6 beta (ATF6-beta)|Protein G13|cAMP response element-binding protein-related protein (Creb-rp)|cAMP-responsive element-binding protein-like 1|Processed cyclic AMP-dependent transcription factor ATF-6 beta|ATF6B|CREBL1|G13

Background: The endoplasmic reticulum (ER)-transmembrane proteins, ATF6 alpha (ATF6) and ATF6 beta (ATF6B), are cleaved during the ER stress response (ERSR). The resulting N-terminal fragments of both ATF6 isoforms, which have conserved basic leucine-zipper and DNA binding domains but divergent transcriptional activation domains, translocate to the nucleus where they bind to ER stress-response elements (ERSE) in ERSR, such as Bip/GRP78. This antibody could recognize ATF6 beta (110kd) and its cleaved forms(60,80kd )(PMID: 11256944)

Poids moléculaire: 110 kDa, 60 kDa, 80 kDa

ID gène: 1388

UniProt: Q99941

Pathways: Thyroid Hormone Synthesis, Myometrial Relaxation and Contraction