alpha 2 Macroglobulin anticorps (AA 1100-1474)

N° du produit ABIN7111503

Cet anticorps anti-alpha 2 Macroglobulin est un anticorps Souris Monoclonal détectant alpha 2 Macroglobulin dans WB, IHC et ELISA. Adapté pour Humain.

Aperçu rapide pour alpha 2 Macroglobulin anticorps (AA 1100-1474) (ABIN7111503)

Antigène: alpha 2 Macroglobulin (A2M) (alpha-2-Macroglobulin (A2M))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp alpha 2 Macroglobulin est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Clone: 6D0

Détail du produit anti-alpha 2 Macroglobulin anticorps

Épitope: AA 1100-1474

Fonction: A2M antibody

Purification: Protein A+G purification

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène:

Immunogen sequence: 1100-1474aa

Immunogen: alpha-2-macroglobulin

Isotype: IgG2a

Information d'application

Indications d'application: WB: 1:500-1:2000, IP: 1:500-1:1000, IF: 1:50-1:500, IHC: 1:20-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur alpha 2 Macroglobulin

Antigène: alpha 2 Macroglobulin (A2M) (alpha-2-Macroglobulin (A2M))

Autre désignation: A2M

Sujet:

Synonyms: Alpha-2-macroglobulin (Alpha-2-M)|C3 and PZP-like alpha-2-macroglobulin domain-containing protein 5|A2M|CPAMD5

Background: Alpha-2-macroglobulin, also known as α2-macroglobulin(α2M or A2M), is a protein abundant in the plasma of vertebrates and several invertebrates. A2M is an evolutionarily conserved arm of the innate immune system. It also mediates the proliferation of T cells and macrophages. A2M acts as a nonspecific protease inhibitor involved in the host defense mechanism that inactivates both endogenous and exogenous proteases, including trypsin, thrombin and collagenase. Even though A2M is produced predominantly by the liver, it may also be expressed in the reproductive tract, heart, and brain, and may have important roles in many physiological processes and medical illnesses including Alzheimer's disease.

Poids moléculaire: 185 kDa

ID gène: 2

UniProt: P01023

Pathways: Lipid Metabolism