Caspase 2 anticorps

N° du produit ABIN7112358

Cet anticorps anti-Caspase 2 Monoclonal Souris (Clone 2B10) (ABIN7112358) détecte spécifiquement Caspase 2 dans WB et ELISA. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour Caspase 2 anticorps (ABIN7112358)

Antigène: Caspase 2 (CASP2) (Caspase 2, Apoptosis-Related Cysteine Peptidase (CASP2))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Caspase 2 est non-conjugé

Application: Western Blotting (WB), ELISA

Clone: 2B10

Détail du produit anti-Caspase 2 anticorps

Fonction: CASP2 antibody

Purification: Protein A+G purification

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: Caspase 2

Isotype: IgG1

Information d'application

Indications d'application: WB: 1:1000-1:6000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur Caspase 2

Antigène: Caspase 2 (CASP2) (Caspase 2, Apoptosis-Related Cysteine Peptidase (CASP2))

Autre désignation: CASP2

Sujet:

Synonyms: Caspase-2 (CASP-2)|Neural precursor cell expressed developmentally down-regulated protein 2 (NEDD-2)|Protease ICH-1|Caspase-2 subunit p18|Caspase-2 subunit p13|Caspase-2 subunit p12|CASP2|ICH1|NEDD2

Background: CASP2(Caspase-2) is also named as ICH1, NEDD2 and belongs to the peptidase C14A family.It is involved in the activation cascade of caspases responsible for apoptosis execution and might function by either activating some proteins required for cell death or inactivating proteins necessary for cell survival.It has 2 isoforms produced by alternative splicing and can exists almost as a dimer in solution(PMID:15865942).This antibody can recognize the 32 kDa pro-caspase 2 as well as 18 kDa cleaved-caspase 2.

Poids moléculaire: 18, 32, 50 kDa

ID gène: 835

UniProt: P42575

Pathways: Apoptose, Caspase Cascade in Apoptosis, Neurotrophin Signaling Pathway