CTNND1 anticorps (AA 470-712)
Aperçu rapide pour CTNND1 anticorps (AA 470-712) (ABIN7112388)
Antigène
Voir toutes CTNND1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 470-712
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Fonction
- CTNND1 antibody
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Purification
- Immunogen affinity purified
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Pureté
- ≥95 % as determined by SDS-PAGE
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Immunogène
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Immunogen sequence: 470-712aa
Immunogen: catenin, delta 1
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Isotype
- IgG
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Indications d'application
- WB: 1:500-1:1000, IP: 1:500-1:1000, IHC: 1:50-1:500, IF: 1:10-1:100
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze / thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- -20°C for 12 months
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Date de péremption
- 12 months
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- CTNND1 (Catenin (Cadherin-Associated Protein), delta 1 (CTNND1))
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Autre désignation
- CTNND1
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Sujet
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Synonyms: Catenin delta-1|Cadherin-associated Src substrate (CAS)|p120 catenin (p120(ctn))|p120(cas)|CTNND1|KIAA0384
Background: Binds to and inhibits the transcriptional repressor ZBTB33, which may lead to activation of target genes of the Wnt signaling pathway(By similarity). Associates with and regulates the cell adhesion properties of both C-, E-and N-cadherins, being critical for their surface stability. Implicated both in cell transformation by SRC and in ligand-induced receptor signaling through the EGF, PDGF, CSF-1 and ERBB2 receptors. Promotes GLIS2 C-terminal cleavage.
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Poids moléculaire
- 105 kDa, 66 kDa
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UniProt
- O60716
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Pathways
- EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Cell-Cell Junction Organization, CXCR4-mediated Signaling Events, Platelet-derived growth Factor Receptor Signaling
Antigène
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