Clusterin anticorps (AA 100-449)

N° du produit ABIN7112893

Cet anticorps Souris Monoclonal détecte spécifiquement Clusterin dans WB, IHC et ELISA. Il présente une réactivité envers Humain.

Aperçu rapide pour Clusterin anticorps (AA 100-449) (ABIN7112893)

Antigène: Clusterin (CLU)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Clusterin est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Clone: 5A5

Détail du produit anti-Clusterin anticorps

Épitope: AA 100-449

Fonction: CLU antibody

Purification: Protein A+G purification

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène:

Immunogen sequence: 100-449aa

Immunogen: clusterin

Isotype: IgG2a

Information d'application

Indications d'application: WB: 1:500-1:2000, IHC: 1:20-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur Clusterin

Antigène: Clusterin (CLU)

Autre désignation: CLU

Sujet:

Synonyms: Clusterin|Aging-associated gene 4 protein|Apolipoprotein J (Apo-J)|Complement cytolysis inhibitor (CLI)|Complement-associated protein SP-40,40|Ku70-binding protein 1|NA1/NA2|Sulfated glycoprotein 2 (SGP-2)|Testosterone-repressed prostate message 2 (TRPM-2)|Clusterin beta chain Alternative names: ApoJalpha|Complement cytolysis inhibitor a chain|SP-40,40 beta-chain|Clusterin alpha chain Alternative names: ApoJbeta|Complement cytolysis inhibitor b chain|SP-40,40 alpha-chain|CLU|APOJ|CLI|KUB1

Background: Clusterin (Apolipoprotein J) is a 75-80 kDa heterodimeric glycoprotein produced by a wide array of tissues and found in most biologic fluids (PMID: 7648419, 11906815). It is encoded by one single gene and cleaved posttranslationally into α (34-36 kDa) and β (36-39 kDa) subunits prior to secretion from the cell. Many functions have been described for clusterin, including regulating apoptosis, transporting lipids, controlling cell interactions, regulating complement (PMID: 10694874).

Poids moléculaire: 36 kDa

ID gène: 1191

UniProt: P10909

Pathways: Apoptose, Negative Regulation of intrinsic apoptotic Signaling