C4BPB anticorps (AA 18-252)

N° du produit ABIN7113013

Cet anticorps Lapin Polyclonal détecte spécifiquement C4BPB dans WB, IHC, ELISA et IF. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour C4BPB anticorps (AA 18-252) (ABIN7113013)

Antigène: C4BPB (Complement Component 4 Binding Protein, beta (C4BPB))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp C4BPB est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Détail du produit anti-C4BPB anticorps

Épitope: AA 18-252

Fonction: C4BPB antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène:

Immunogen sequence: 18-252aa

Immunogen: complement component 4 binding protein, beta

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500 - 1:2000, IHC: 1:50 - 1:100, IF: 1:50 - 1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur C4BPB

Antigène: C4BPB (Complement Component 4 Binding Protein, beta (C4BPB))

Autre désignation: C4BPB

Sujet:

Synonyms: C4b-binding protein beta chain|C4BPB

Background: This gene encodes a member of a superfamily of proteins composed predominantly of tandemly arrayed short consensus repeats of approximately 60 amino acids. A single, unique beta-chain encoded by this gene assembles with seven identical alpha-chains into the predominant isoform of C4b-binding protein, a multimeric protein that controls activation of the complement cascade through the classical pathway. C4b-binding protein has a regulatory role in the coagulation system also, mediated through the beta-chain binding of protein S, a vitamin K-dependent protein that serves as a cofactor of activated protein C. The genes encoding both alpha and beta chains are located adjacent to each other on human chromosome 1 in the regulator of complement activation gene cluster. Alternative splicing gives rise to multiple transcript variants.

Poids moléculaire: 40-45 kDa

ID gène: 725

UniProt: P20851

Pathways: Système du Complément