C5AR1 anticorps
Aperçu rapide pour C5AR1 anticorps (ABIN7113014)
Antigène
Voir toutes C5AR1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- C5AR1 antibody
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Purification
- Immunogen affinity purified
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Pureté
- ≥95 % as determined by SDS-PAGE
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Immunogène
- complement component 5a receptor 1
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Isotype
- IgG
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Indications d'application
- WB: 1:500-1:2000, IP: 1:500-1:1000, IHC: 1:20-1:200, IF: 1:10-1:100
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze / thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- -20°C for 12 months
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Date de péremption
- 12 months
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- C5AR1 (Complement Component 5a Receptor 1 (C5AR1))
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Autre désignation
- C5AR1
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Sujet
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Synonyms: C5a anaphylatoxin chemotactic receptor 1|C5a anaphylatoxin chemotactic receptor (C5a-R, C5aR)|C5AR1|C5AR|C5R1
Background: Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a(PubMed:1847994, PubMed:8182049, PubMed:7622471, PubMed:9553099, PubMed:10636859, PubMed:15153520). The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N-terminus, and a second site in the transmembrane region which activates downstream signaling events(PubMed:8182049, PubMed:7622471, PubMed:9553099). Receptor activation stimulates chemotaxis, granule enzyme release, intracellular calcium release and superoxide anion production(PubMed:10636859, PubMed:15153520).
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Poids moléculaire
- 45-50 kDa
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ID gène
- 728
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UniProt
- P21730
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Pathways
- Système du Complément
Antigène
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