Cytochrome C anticorps
Aperçu rapide pour Cytochrome C anticorps (ABIN7113248)
Antigène
Voir toutes Cytochrome C (CYCS) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Fonction
- CYCS antibody
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Purification
- Protein A+G purification
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Pureté
- ≥95 % as determined by SDS-PAGE
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Immunogène
- Cytochrome c
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Isotype
- IgG2a
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Indications d'application
- WB: 1:5000-1:30000, IHC: 1:100-1:1000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze / thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- -20°C for 12 months
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Date de péremption
- 12 months
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- Cytochrome C (CYCS) (Cytochrome C, Somatic (CYCS))
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Autre désignation
- CYCS
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Sujet
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Synonyms: Cytochrome c|CYCS|CYC
Background: Cytochrome c is a 12-15 kDa electron transporting protein located in the inner mitochondrial membrane. Upon apoptotic stimulation, cytochrome c can be released from mitochondria into cytoplasm, resulting in caspase-3 activation and apoptosis. Measurement of cytochrome c release from the mitochondria is useful for detection of the onset of apoptosis in cells. In addition, cytochrome c can also leave cells and be detectable in extra-cellular medium of apoptotic cells and serum of cancer patients. The level of serum cytochrome c may serve as a prognostic maker during cancer therapy.
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Poids moléculaire
- 12 kDa
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ID gène
- 54205
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UniProt
- P99999
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Pathways
- Apoptose, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity
Antigène
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