DKK2 anticorps
Aperçu rapide pour DKK2 anticorps (ABIN7113473)
Antigène
Voir toutes DKK2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- DKK2 antibody
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Purification
- Immunogen affinity purified
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Pureté
- ≥95 % as determined by SDS-PAGE
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Immunogène
- dickkopf homolog 2
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Isotype
- IgG
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Indications d'application
- WB: 1:500-1:1000, IHC: 1:20-1:200
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze / thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- -20°C for 12 months
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Date de péremption
- 12 months
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- DKK2 (Dickkopf 2 Homolog (DKK2))
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Autre désignation
- DKK2
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Sujet
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Synonyms: Dickkopf-related protein 2 (Dickkopf-2, Dkk-2, hDkk-2)|DKK2
Background: Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease(By similarity).
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Poids moléculaire
- 32 kDa
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ID gène
- 27123
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UniProt
- Q9UBU2
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Pathways
- Signalisation WNT
Antigène
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