ERCC6 anticorps

N° du produit ABIN7113989

L’anticorps anti-ERCC6 Polyclonal produit chez le Lapin a été validé pour WB et ELISA. Il convient pour la détection de ERCC6 dans des échantillons provenant de Humain, Rat et Souris. }

Aperçu rapide pour ERCC6 anticorps (ABIN7113989)

Antigène: ERCC6 (Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 6 (ERCC6))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ERCC6 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-ERCC6 anticorps

Fonction: ERCC6 antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: excision repair cross-complementing rodent repair deficiency, complementation group 6

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur ERCC6

Antigène: ERCC6 (Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 6 (ERCC6))

Autre désignation: ERCC6

Sujet:

Synonyms: DNA excision repair protein ERCC-6|ATP-dependent helicase ERCC6|Cockayne syndrome protein CSB|ERCC6|CSB

Background: Essential factor involved in transcription-coupled nucleotide excision repair which allows RNA polymerase II-blocking lesions to be rapidly removed from the transcribed strand of active genes. Upon DNA-binding, it locally modifies DNA conformation by wrapping the DNA around itself, thereby modifying the interface between stalled RNA polymerase II and DNA. It is required for transcription-coupled repair complex formation. It recruits the CSA complex(DCX(ERCC8) complex), nucleotide excision repair proteins and EP300 to the at sites of RNA polymerase II-blocking lesions.

Poids moléculaire: 150 kDa

ID gène: 2074

UniProt: Q03468

Pathways: Réparation de l'ADN, Chromatin Binding