ERCC6 anticorps (Internal Region)

N° du produit ABIN2855858

Détail du produit anti-ERCC6 anticorps

Antigène: ERCC6 (Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 6 (ERCC6))

Épitope: Internal Region

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ERCC6 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Immunocytochemistry (ICC)

Attributs du produit: Rabbit Polyclonal antibody to CSB (excision repair cross-complementing rodent repair deficiency, complementation group 6)
CSB antibody [N2C1], Internal

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein encompassing a sequence within the center region of human CSB. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: Suggested dilution Reference ICC/IF 1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Immunoprecipitation 1:100-1:500* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Immunoprecipitation1:100-1:500* Western blot1:500-1:3000*

Commentaires:

Positive Control: 293T , A431 , HeLa , HepG2

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 1XPBS, 0.2M Tris, 0.2M Glycine, 1 mM EGTA, 50 % Glycerol ( pH 7). 0.025 % ProClin 300 was added as a preservative.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Détails sur ERCC6

Antigène: ERCC6 (Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 6 (ERCC6))

Autre désignation: CSB (ERCC6 Produits)

Synonymes: anticorps ARMD5, anticorps CKN2, anticorps COFS, anticorps COFS1, anticorps CSB, anticorps RAD26, anticorps UVSS1, anticorps 4732403I04, anticorps C130058G22Rik, anticorps ercc6, anticorps Ercc6, anticorps ERCC excision repair 6, chromatin remodeling factor, anticorps excision repair cross-complementing rodent repair deficiency, complementation group 6, anticorps excision repair cross-complementation group 6, anticorps DNA excision repair protein ERCC-6, anticorps ERCC6, anticorps Ercc6, anticorps ercc6, anticorps LOC100719487

Sujet: This gene encodes a DNA-binding protein that is important in transcription-coupled excision repair. The protein has ATP-stimulated ATPase activity, there are contradictory publications reporting presence or absence of helicase activity. The protein appears to interact with several transcription and excision repair proteins, and may promote complex formation at repair sites. Mutations in this gene result in Cockayne syndrome type B.

Cellular Localization: Nucleus

Poids moléculaire: 168 kDa

ID gène: 2074

Pathways: Réparation de l'ADN, Chromatin Binding