FANCL anticorps

N° du produit ABIN7114121

L’anticorps Lapin Polyclonal anti-FANCL a été validé pour WB, ELISA et IHC. Il convient pour détecter FANCL dans des échantillons de Humain et Souris.

Aperçu rapide pour FANCL anticorps (ABIN7114121)

Antigène: FANCL (Fanconi Anemia, Complementation Group L (FANCL))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FANCL est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-FANCL anticorps

Fonction: FANCL antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: Fanconi anemia, complementation group L

Isotype: IgG

Information d'application

Indications d'application: WB: 1:200 - 1:2000, IHC: 1:20 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur FANCL

Antigène: FANCL (Fanconi Anemia, Complementation Group L (FANCL))

Autre désignation: FANCL

Sujet:

Synonyms: E3 ubiquitin-protein ligase FANCL|Fanconi anemia group L protein|Fanconi anemia-associated polypeptide of 43 kDa (FAAP43)|RING-type E3 ubiquitin transferase FANCL|FANCL|PHF9

Background: The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity, they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group L. Alternative splicing results in two transcript variants encoding different isoforms.

Poids moléculaire: 38 kDa

ID gène: 55120

UniProt: Q9NW38

Pathways: Réparation de l'ADN