IFNAR2 anticorps

N° du produit ABIN7115355

Cet anticorps anti-IFNAR2 est un anticorps Lapin Polyclonal détectant IFNAR2 dans WB, ELISA et IF. Adapté pour Humain, Souris et Rat.

Aperçu rapide pour IFNAR2 anticorps (ABIN7115355)

Antigène: IFNAR2 (Interferon alpha/beta Receptor 2 (IFNAR2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IFNAR2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Détail du produit anti-IFNAR2 anticorps

Fonction: IFNAR2 antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: interferon(alpha, beta and omega) receptor 2

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur IFNAR2

Antigène: IFNAR2 (Interferon alpha/beta Receptor 2 (IFNAR2))

Autre désignation: IFNAR2

Sujet:

Synonyms: Interferon alpha/beta receptor 2 (IFN-R-2, IFN-alpha binding protein, IFN-alpha/beta receptor 2)|Interferon alpha binding protein|Type I interferon receptor 2|IFNAR2|IFNABR|IFNARB

Background: Associates with IFNAR1 to form the type I interferon receptor. Receptor for interferons alpha and beta. Involved in IFN-mediated STAT1, STAT2 and STAT3 activation(PubMed:26424569). Isoform 1 and isoform 2 are directly involved in signal transduction due to their association with the TYR kinase, JAK1(PubMed:8181059, PubMed:7665574, PubMed:7759950). Isoform 3 is a potent inhibitor of type I IFN receptor activity(PubMed:7759950).

Poids moléculaire: 58-66 kDa

ID gène: 3455

UniProt: P48551

Pathways: Signalistation JAK/STAT, Hepatitis C