IRF9 anticorps

N° du produit ABIN7115377

Cet anticorps Lapin Polyclonal détecte spécifiquement IRF9 dans WB, ELISA, IHC, IF et IP. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour IRF9 anticorps (ABIN7115377)

Antigène: IRF9 (Interferon Regulatory Factor 9 (IRF9))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IRF9 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)

Détail du produit anti-IRF9 anticorps

Fonction: IRF9 antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: interferon regulatory factor 9

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:1000, IP: 1:500-1:1000, IHC: 1:50-1:500, IF: 1:20-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur IRF9

Antigène: IRF9 (Interferon Regulatory Factor 9 (IRF9))

Autre désignation: IRF9

Sujet:

Synonyms: Interferon regulatory factor 9 (IRF-9)|IFN-alpha-responsive transcription factor subunit|ISGF3 p48 subunit|Interferon-stimulated gene factor 3 gamma (ISGF-3 gamma)|Transcriptional regulator ISGF3 subunit gamma|IRF9|ISGF3G

Background: Transcription factor that mediates signaling by type I IFNs(IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors, Jak kinases(TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. IRF9/ISGF3G associates with the phosphorylated STAT1:STAT2 dimer to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element(ISRE) to activate the transcription of interferon stimulated genes, which drive the cell in an antiviral state.

Poids moléculaire: 48 kDa

ID gène: 10379

UniProt: Q00978

Pathways: Signalistation JAK/STAT, Interferon-gamma Pathway, Hepatitis C