IL23A anticorps (AA 20-189)

N° du produit ABIN7115450

L’anticorps Souris Monoclonal anti-IL23A a été validé pour WB, ELISA et IHC. Il convient pour détecter IL23A dans des échantillons de Humain.

Aperçu rapide pour IL23A anticorps (AA 20-189) (ABIN7115450)

Antigène: IL23A (Interleukin 23, alpha subunit p19 (IL23A))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp IL23A est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Clone: 2G1

Détail du produit anti-IL23A anticorps

Épitope: AA 20-189

Fonction: IL23A antibody

Purification: Protein A+G purification

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène:

Immunogen sequence: 20-189aa

Immunogen: interleukin 23, alpha subunit p19

Isotype: IgG1

Information d'application

Indications d'application: WB: 1:500-1:2000, IHC: 1:20-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur IL23A

Antigène: IL23A (Interleukin 23, alpha subunit p19 (IL23A))

Autre désignation: IL23A

Sujet:

Synonyms: Interleukin-23 subunit alpha (IL-23 subunit alpha, IL-23-A)|Interleukin-23 subunit p19 (IL-23p19)|IL23A|SGRF

Background: Associates with IL12B to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis.

Poids moléculaire: 21 kDa

ID gène: 51561

UniProt: Q9NPF7

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation