IL-6 Receptor anticorps

N° du produit ABIN7115473

Cet anticorps Lapin Polyclonal détecte spécifiquement IL-6 Receptor dans WB, IHC, IP et ELISA. Il présente une réactivité envers Humain, Rat et Souris.

Aperçu rapide pour IL-6 Receptor anticorps (ABIN7115473)

Antigène: IL-6 Receptor (IL6R) (Interleukin 6 Receptor (IL6R))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IL-6 Receptor est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), ELISA

Détail du produit anti-IL-6 Receptor anticorps

Fonction: IL6R antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène:

Immunogen sequence: P08887-1,229-468

Immunogen: interleukin 6 receptor

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:1000, IHC: 1:50-1:200, IP: 1:500-1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur IL-6 Receptor

Antigène: IL-6 Receptor (IL6R) (Interleukin 6 Receptor (IL6R))

Autre désignation: IL6R

Sujet:

Synonyms: Interleukin-6 receptor subunit alpha (IL-6 receptor subunit alpha, IL-6R subunit alpha, IL-6R-alpha, IL-6RA)|IL-6R 1|Membrane glycoprotein 80 (gp80)|Soluble interleukin-6 receptor subunit alpha (sIL6R)|IL6R

Background: Part of the receptor for interleukin 6. Binds to IL6 with low affinity, but does not transduce a signal. Signal activation necessitate an association with IL6ST. Activation may lead to the regulation of the immune response, acute-phase reactions and hematopoiesis. Low concentration of a soluble form of IL6 receptor acts as an agonist of IL6 activity.

Poids moléculaire: 80 kDa

ID gène: 3570

UniProt: P08887

Pathways: Signalistation JAK/STAT, Autophagy, Growth Factor Binding, Cancer Immune Checkpoints