IFT57 anticorps

N° du produit ABIN7115495

L’anticorps anti-IFT57 Polyclonal produit chez le Lapin a été validé pour WB, IHC, ELISA et IP. Il convient pour la détection de IFT57 dans des échantillons provenant de Humain, Souris et Rat. }

Aperçu rapide pour IFT57 anticorps (ABIN7115495)

Antigène: IFT57 (Intraflagellar Transport 57 Homolog (IFT57))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IFT57 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP)

Détail du produit anti-IFT57 anticorps

Fonction: IFT57 antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: intraflagellar transport 57 homolog(Chlamydomonas)

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:2000, IP: 1:200-1:1000, IHC: 1:20-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur IFT57

Antigène: IFT57 (Intraflagellar Transport 57 Homolog (IFT57))

Autre désignation: IFT57

Sujet:

Synonyms: Intraflagellar transport protein 57 homolog|Dermal papilla-derived protein 8|Estrogen-related receptor beta-like protein 1|HIP1-interacting protein|MHS4R2|IFT57|DERP8|ESRRBL1|HIPPI

Background: Required for the formation of cilia. Plays an indirect role in sonic hedgehog signaling, cilia being required for all activity of the hedgehog pathway(By similarity). Has pro-apoptotic function via its interaction with HIP1, leading to recruit caspase-8(CASP8) and trigger apoptosis. Has the ability to bind DNA sequence motif 5'-AAAGACATG-3' present in the promoter of caspase genes such as CASP1, CASP8 and CASP10, suggesting that it may act as a transcription regulator, however the relevance of such function remains unclear.

Poids moléculaire: 49 kDa

ID gène: 55081

UniProt: Q9NWB7

Pathways: Signalisation Hedgehog, Positive Regulation of Endopeptidase Activity