MIA3 anticorps

N° du produit ABIN7116180

Cet anticorps anti-MIA3 Polyclonal Lapin (ABIN7116180) détecte spécifiquement MIA3 dans ELISA, WB et IP. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour MIA3 anticorps (ABIN7116180)

Antigène: MIA3 (Melanoma Inhibitory Activity Family, Member 3 (MIA3))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MIA3 est non-conjugé

Application: ELISA, Western Blotting (WB), Immunoprecipitation (IP)

Détail du produit anti-MIA3 anticorps

Fonction: MIA3 antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: melanoma inhibitory activity family, member 3

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:2000, IP: 1:200-1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur MIA3

Antigène: MIA3 (Melanoma Inhibitory Activity Family, Member 3 (MIA3))

Autre désignation: MIA3

Sujet:

Synonyms: Transport and Golgi organization protein 1 homolog (TANGO1)|C219-reactive peptide|D320|Melanoma inhibitory activity protein 3|MIA3|KIAA0268|TANGO

Background: Plays a role in the transport of cargos that are too large to fit into COPII-coated vesicles and require specific mechanisms to be incorporated into membrane-bound carriers and exported from the endoplasmic reticulum. This protein is required for collagen VII(COL7A1) secretion by loading COL7A1 into transport carriers. It may participate in cargo loading of COL7A1 at endoplasmic reticulum exit sites by binding to COPII coat subunits Sec23/24 and guiding SH3-bound COL7A1 into a growing carrier. Does not play a role in global protein secretion and is apparently specific to COL7A1 cargo loading. However, it may participate in secretion of other proteins in cells that do not secrete COL7A1. It is also specifically required for the secretion of lipoproteins by participating in their export from the endoplasmic reticulum(PubMed:27138255).

Poids moléculaire: 250-300 kDa

ID gène: 375056

UniProt: Q5JRA6