MITF anticorps

N° du produit ABIN7116282

Cet anticorps anti-MITF est un anticorps Polyclonal produit chez le Lapin, détectant MITF dans WB, FACS, ELISA et IP. Convient pour Humain, Souris et Rat.

Aperçu rapide pour MITF anticorps (ABIN7116282)

Antigène: MITF (Microphthalmia-Associated Transcription Factor (MITF))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MITF est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), ELISA, Immunoprecipitation (IP)

Détail du produit anti-MITF anticorps

Fonction: MITF antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: microphthalmia-associated transcription factor

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:2000, IP: 1:500-1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur MITF

Antigène: MITF (Microphthalmia-Associated Transcription Factor (MITF))

Autre désignation: MITF

Sujet:

Synonyms: Microphthalmia-associated transcription factor|Class E basic helix-loop-helix protein 32 (bHLHe32)|MITF|BHLHE32

Background: Transcription factor that regulates the expression of genes with essential roles in cell differentiation, proliferation and survival. Binds to symmetrical DNA sequences(E-boxes)(5'-CACGTG-3') found in the promoters of target genes, such as BCL2 and tyrosinase(TYR). Plays an important role in melanocyte development by regulating the expression of tyrosinase(TYR) and tyrosinase-related protein 1(TYRP1). Plays a critical role in the differentiation of various cell types, such as neural crest-derived melanocytes, mast cells, osteoclasts and optic cup-derived retinal pigment epithelium.

Poids moléculaire: 60-65 kDa

ID gène: 4286

UniProt: O75030

Pathways: Chromatin Binding