MCM5 anticorps

N° du produit ABIN7116313

Cet anticorps Lapin Polyclonal détecte spécifiquement MCM5 dans WB, IHC, ELISA et IP. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour MCM5 anticorps (ABIN7116313)

Antigène: MCM5 (Minichromosome Maintenance Complex Component 5 (MCM5))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MCM5 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP)

Détail du produit anti-MCM5 anticorps

Fonction: MCM5 antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: minichromosome maintenance complex component 5

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:2000, IP: 1:200-1:1000, IHC: 1:20-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur MCM5

Antigène: MCM5 (Minichromosome Maintenance Complex Component 5 (MCM5))

Autre désignation: MCM5

Sujet:

Synonyms: DNA replication licensing factor MCM5|CDC46 homolog|P1-CDC46|MCM5|CDC46

Background: Acts as component of the MCM2-7 complex(MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity(By similarity). Interacts with MCMBP.

Poids moléculaire: 82 kDa

ID gène: 4174

UniProt: P33992

Pathways: Réparation de l'ADN, Mitotic G1-G1/S Phases, DNA Replication, Chromatin Binding, Synthesis of DNA