NSUN2 anticorps

N° du produit ABIN7116925

Cet anticorps Lapin Polyclonal détecte spécifiquement NSUN2 dans WB, ELISA, IHC et IF. Il présente une réactivité envers Humain et Souris.

Aperçu rapide pour NSUN2 anticorps (ABIN7116925)

Antigène: NSUN2 (NOP2/Sun Domain Family, Member 2 (NSUN2))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NSUN2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-NSUN2 anticorps

Fonction: NSUN2 antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: NOL1/NOP2/Sun domain family, member 2

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:2000, IHC: 1:20-1:200, IF: 1:20-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur NSUN2

Antigène: NSUN2 (NOP2/Sun Domain Family, Member 2 (NSUN2))

Autre désignation: NSUN2

Sujet:

Synonyms: RNA cytosine C(5)-methyltransferase NSUN2|Myc-induced SUN domain-containing protein (Misu)|NOL1/NOP2/Sun domain family member 2|Substrate of AIM1/Aurora kinase B|mRNA cytosine C(5)-methyltransferase|tRNA cytosine C(5)-methyltransferase|tRNA methyltransferase 4 homolog (hTrm4)|NSUN2|SAKI|TRM4

Background: RNA methyltransferase that methylates tRNAs, and possibly RNA polymerase III transcripts. Methylates cytosine to 5-methylcytosine(m5C) at positions 34 and 48 of intron-containing tRNA(Leu)(CAA) precursors, and at positions 48, 49 and 50 of tRNA(Gly)(GCC) precursors. May act downstream of Myc to regulate epidermal cell growth and proliferation. Required for proper spindle assembly and chromosome segregation, independently of its methyltransferase activity.

Poids moléculaire: 90-100 kDa

ID gène: 54888

UniProt: Q08J23