NFX1 anticorps
Aperçu rapide pour NFX1 anticorps (ABIN7117021)
Antigène
Voir toutes NFX1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- NFX1 antibody
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Purification
- Immunogen affinity purified
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Pureté
- ≥95 % as determined by SDS-PAGE
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Immunogène
- nuclear transcription factor, X-box binding 1
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Isotype
- IgG
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Indications d'application
- WB: 1:500-1:2000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze / thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- -20°C for 12 months
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Date de péremption
- 12 months
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- NFX1 (Nuclear Transcription Factor, X-Box Binding 1 (NFX1))
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Autre désignation
- NFX1
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Sujet
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Synonyms: Transcriptional repressor NF-X1|Nuclear transcription factor, X box-binding protein 1|NFX1|NFX2
Background: Binds to the X-box motif of MHC class II genes and represses their expression. May play an important role in regulating the duration of an inflammatory response by limiting the period in which MHC class II molecules are induced by interferon-gamma. Isoform 3 binds to the X-box motif of TERT promoter and represses its expression. Together with PABPC1 or PABPC4, isoform 1 acts as a coactivator for TERT expression. Mediates E2-dependent ubiquitination.
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Poids moléculaire
- 124 kDa
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ID gène
- 4799
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UniProt
- Q12986
Antigène
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