PASK anticorps

N° du produit ABIN7117245

Cet anticorps anti-PASK Polyclonal Lapin (ABIN7117245) détecte spécifiquement PASK dans WB, ELISA, IF et IHC. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour PASK anticorps (ABIN7117245)

Antigène: PASK (PAS Domain Containing Serine/threonine Kinase (PASK))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PASK est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC)

Détail du produit anti-PASK anticorps

Fonction: PASK antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: PAS domain containing serine/threonine kinase

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:2000, IHC: 1:20-1:200, IF: 1:20-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur PASK

Antigène: PASK (PAS Domain Containing Serine/threonine Kinase (PASK))

Autre désignation: PASK

Sujet:

Synonyms: PAS domain-containing serine/threonine-protein kinase (PAS-kinase, PASKIN, hPASK)|PASK|KIAA0135

Background: Serine/threonine-protein kinase involved in energy homeostasis and protein translation. Phosphorylates EEF1A1, GYS1, PDX1 and RPS6. Probably plays a role under changing environmental conditions(oxygen, glucose, nutrition), rather than under standard conditions. Acts as a sensor involved in energy homeostasis: regulates glycogen synthase synthesis by mediating phosphorylation of GYS1, leading to GYS1 inactivation. May be involved in glucose-stimulated insulin production in pancreas and regulation of glucagon secretion by glucose in alpha cells, however such data require additional evidences. May play a role in regulation of protein translation by phosphorylating EEF1A1, leading to increase translation efficiency. May also participate to respiratory regulation.

Poids moléculaire: 180 kDa

ID gène: 23178

UniProt: Q96RG2

Pathways: Regulation of Carbohydrate Metabolic Process