POLK anticorps
Aperçu rapide pour POLK anticorps (ABIN7117655)
Antigène
Voir toutes POLK AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- POLK antibody
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Purification
- Immunogen affinity purified
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Pureté
- ≥95 % as determined by SDS-PAGE
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Immunogène
- polymerase(DNA directed) kappa
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Isotype
- IgG
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Indications d'application
- WB: 1:500-1:2000, IHC: 1:20-1:200
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze / thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- -20°C for 12 months
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Date de péremption
- 12 months
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- POLK (Polymerase (DNA Directed) kappa (POLK))
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Autre désignation
- POLK
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Sujet
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Synonyms: DNA polymerase kappa|DINB protein (DINP)|POLK|DINB1
Background: DNA polymerase specifically involved in DNA repair. Plays an important role in translesion synthesis, where the normal high-fidelity DNA polymerases cannot proceed and DNA synthesis stalls. Depending on the context, it inserts the correct base, but causes frequent base transitions, transversions and frameshifts. Lacks 3'-5' proofreading exonuclease activity. Forms a Schiff base with 5'-deoxyribose phosphate at abasic sites, but does not have lyase activity.
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Poids moléculaire
- 70 kDa
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ID gène
- 51426
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UniProt
- Q9UBT6
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Pathways
- Réparation de l'ADN
Antigène
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