PPM1A anticorps
Aperçu rapide pour PPM1A anticorps (ABIN7118037)
Antigène
Voir toutes PPM1A AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- PPM1A antibody
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Purification
- Immunogen affinity purified
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Pureté
- ≥95 % as determined by SDS-PAGE
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Immunogène
- protein phosphatase 1A(formerly 2C), magnesium-dependent, alpha isoform
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Isotype
- IgG
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Indications d'application
- WB: 1:500-1:2000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze / thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- -20°C for 12 months
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Date de péremption
- 12 months
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- PPM1A (Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A (PPM1A))
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Autre désignation
- PPM1A
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Sujet
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Synonyms: Protein phosphatase 1A|Protein phosphatase 2C isoform alpha (PP2C-alpha)|Protein phosphatase IA|PPM1A|PPPM1A
Background: Enzyme with a broad specificity. Negatively regulates TGF-beta signaling through dephosphorylating SMAD2 and SMAD3, resulting in their dissociation from SMAD4, nuclear export of the SMADs and termination of the TGF-beta-mediated signaling. Dephosphorylates PRKAA1 and PRKAA2. Plays an important role in the termination of TNF-alpha-mediated NF-kappa-B activation through dephosphorylating and inactivating IKBKB/IKKB.
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Poids moléculaire
- 42 kDa
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ID gène
- 5494
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UniProt
- P35813
Antigène
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