RAD23A anticorps

N° du produit ABIN7118252

L’anticorps Lapin Polyclonal anti-RAD23A a été validé pour WB, ELISA, IHC et IP. Il convient pour détecter RAD23A dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour RAD23A anticorps (ABIN7118252)

Antigène: RAD23A (RAD23 Homolog A (RAD23A))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RAD23A est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)

Détail du produit anti-RAD23A anticorps

Fonction: RAD23A antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: RAD23 homolog A

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:2000, IP: 1:200-1:1000, IHC: 1:20-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur RAD23A

Antigène: RAD23A (RAD23 Homolog A (RAD23A))

Autre désignation: RAD23A

Sujet:

Synonyms: UV excision repair protein RAD23 homolog A (HR23A, hHR23A)|RAD23A

Background: Multiubiquitin chain receptor involved in modulation of proteasomal degradation. Binds to 'Lys-48'-linked polyubiquitin chains in a length-dependent manner and with a lower affinity to 'Lys-63'-linked polyubiquitin chains. Proposed to be capable to bind simultaneously to the 26S proteasome and to polyubiquitinated substrates and to deliver ubiquitinated proteins to the proteasome. Involved in nucleotide excision repair and is thought to be functional equivalent for RAD23B in global genome nucleotide excision repair(GG-NER) by association with XPC. In vitro, the XPC:RAD23A dimer has NER activity. Can stabilize XPC. Involved in vpr-dependent replication of HIV-1 in non-proliferating cells and primary macrophages. Required for the association of HIV-1 vpr with the host proteasome.

Poids moléculaire: 55 kDa

ID gène: 5886

UniProt: P54725

Pathways: Réparation de l'ADN