RASIP1 anticorps
Aperçu rapide pour RASIP1 anticorps (ABIN7118312)
Antigène
Voir toutes RASIP1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- RASIP1 antibody
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Purification
- Immunogen affinity purified
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Pureté
- ≥95 % as determined by SDS-PAGE
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Immunogène
- Ras interacting protein 1
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Isotype
- IgG
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Indications d'application
- WB: 1:500-1:2000, IHC: 1:20-1:200, IF: 1:20-1:200
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze / thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- -20°C for 12 months
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Date de péremption
- 12 months
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- RASIP1 (Ras Interacting Protein 1 (RASIP1))
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Autre désignation
- RASIP1
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Sujet
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Synonyms: Ras-interacting protein 1 (Rain)|RASIP1
Background: Required for the proper formation of vascular structures that develop via both vasculogenesis and angiogenesis. Acts as a critical and vascular-specific regulator of GTPase signaling, cell architecture, and adhesion, which is essential for endothelial cell morphogenesis and blood vessel tubulogenesis. Regulates the activity of Rho GTPases in part by recruiting ARHGAP29 and suppressing RhoA signaling and dampening ROCK and MYH9 activities in endothelial cells(By similarity). May act as effector for Golgi-bound HRAS and other Ras-like proteins. May promote HRAS-mediated transformation. Negative regulator of amino acid starvation-induced autophagy.
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Poids moléculaire
- 115 kDa
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ID gène
- 54922
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UniProt
- Q5U651
Antigène
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