RHBDD1 anticorps

N° du produit ABIN7118505

Cet anticorps anti-RHBDD1 est un anticorps Lapin Polyclonal détectant RHBDD1 dans WB et ELISA. Adapté pour Humain, Souris et Rat.

Aperçu rapide pour RHBDD1 anticorps (ABIN7118505)

Antigène: RHBDD1 (Rhomboid Domain Containing 1 (RHBDD1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RHBDD1 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-RHBDD1 anticorps

Fonction: RHBDD1 antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: rhomboid domain containing 1

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur RHBDD1

Antigène: RHBDD1 (Rhomboid Domain Containing 1 (RHBDD1))

Autre désignation: RHBDD1

Sujet:

Synonyms: Rhomboid-related protein 4 (RRP4)|Rhomboid domain-containing protein 1|Rhomboid-like protein 4|RHBDD1|RHBDL4

Background: Intramembrane-cleaving serine protease that cleaves single transmembrane or multi-pass membrane proteins in the hydrophobic plane of the membrane, luminal loops and juxtamembrane regions. Involved in regulated intramembrane proteolysis and the subsequent release of functional polypeptides from their membrane anchors. Functional component of endoplasmic reticulum-associated degradation(ERAD) for misfolded membrane proteins. Required for the degradation process of some specific misfolded endoplasmic reticulum(ER) luminal proteins. Participates in the transfer of misfolded proteins from the ER to the cytosol, where they are destroyed by the proteasome in a ubiquitin-dependent manner. Functions in BIK, MPZ, PKD1, PTCRA, RHO, STEAP3 and TRAC processing. Involved in the regulation of exosomal secretion, inhibits the TSAP6-mediated secretion pathway. Involved in the regulation of apoptosis, modulates BIK-mediated apoptotic activity. Also plays a role in the regulation of spermatogenesis, inhibits apoptotic activity in spermatogonia.

Poids moléculaire: 36 kDa

ID gène: 84236

UniProt: Q8TEB9