SH3BP4 anticorps (AA 615-963)

N° du produit ABIN7119024

Cet anticorps anti-SH3BP4 est un anticorps Lapin Polyclonal détectant SH3BP4 dans WB, ELISA, IP et IF. Adapté pour Humain, Souris et Rat.

Aperçu rapide pour SH3BP4 anticorps (AA 615-963) (ABIN7119024)

Antigène: SH3BP4 (SH3-Domain Binding Protein 4 (SH3BP4))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SH3BP4 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunoprecipitation (IP), Immunofluorescence (IF)

Détail du produit anti-SH3BP4 anticorps

Épitope: AA 615-963

Fonction: SH3BP4 antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène:

Immunogen sequence: 615-963aa

Immunogen: SH3-domain binding protein 4

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:2000, IP: 1:200-1:1000, IF: 1:20-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur SH3BP4

Antigène: SH3BP4 (SH3-Domain Binding Protein 4 (SH3BP4))

Autre désignation: SH3BP4

Sujet:

Synonyms: SH3 domain-binding protein 4|EH-binding protein 10|Transferrin receptor-trafficking protein|SH3BP4|BOG25|EHB10|TTP

Background: May function in transferrin receptor internalization at the plasma membrane through a cargo-specific control of clathrin-mediated endocytosis. Alternatively, may act as a negative regulator of the amino acid-induced TOR signaling by inhibiting the formation of active Rag GTPase complexes. Preferentially binds inactive Rag GTPase complexes and prevents their interaction with the mTORC1 complex inhibiting its relocalization to lysosomes and its activation. Thereby, may indirectly regulate cell growth, proliferation and autophagy.

Poids moléculaire: 120 kDa

ID gène: 23677

UniProt: Q9P0V3