STAT4 anticorps
Aperçu rapide pour STAT4 anticorps (ABIN7119082)
Antigène
Voir toutes STAT4 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- STAT4 antibody
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Purification
- Immunogen affinity purified
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Pureté
- ≥95 % as determined by SDS-PAGE
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Immunogène
- signal transducer and activator of transcription 4
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Isotype
- IgG
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Indications d'application
- WB: 1:500 - 1:2000, IHC: 1:50 - 1:200, IF: 1:50 - 1:100
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze / thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- -20°C for 12 months
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Date de péremption
- 12 months
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- STAT4 (Signal Transducer and Activator of Transcription 4 (STAT4))
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Autre désignation
- STAT4
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Sujet
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Synonyms: Signal transducer and activator of transcription 4|STAT4
Background: The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is essential for mediating responses to IL12 in lymphocytes, and regulating the differentiation of T helper cells. Mutations in this gene may be associated with systemic lupus erythematosus and rheumatoid arthritis. Alternate splicing results in multiple transcript variants that encode the same protein.
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Poids moléculaire
- 85 kDa
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ID gène
- 6775
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UniProt
- Q14765
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Pathways
- Signalistation JAK/STAT
Antigène
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