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SLC22A1 anticorps

SLC22A1 Reactivité: Humain, Souris, Rat WB, ELISA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN7119250
  • Antigène Voir toutes SLC22A1 Anticorps
    SLC22A1 (Solute Carrier Family 22 (Organic Cation Transporter), Member 1 (SLC22A1))
    Reactivité
    • 47
    • 8
    • 7
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    Humain, Souris, Rat
    Hôte
    • 39
    • 9
    • 1
    Lapin
    Clonalité
    • 40
    • 9
    Polyclonal
    Conjugué
    • 22
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Cet anticorp SLC22A1 est non-conjugé
    Application
    • 31
    • 23
    • 17
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA
    Purification
    Immunogen affinity purified
    Pureté
    ≥95 % as determined by SDS-PAGE
    Immunogène
    solute carrier family 22(organic cation transporter), member 1
    Isotype
    IgG
    Top Product
    Discover our top product SLC22A1 Anticorps primaire
  • Indications d'application
    WB: 1:500-1:2000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    Date de péremption
    12 months
  • Antigène
    SLC22A1 (Solute Carrier Family 22 (Organic Cation Transporter), Member 1 (SLC22A1))
    Autre désignation
    SLC22A1 (SLC22A1 Produits)
    Synonymes
    anticorps SLC22A1, anticorps OCT1, anticorps HOCT1, anticorps oct1_cds, anticorps Lx1, anticorps Oct1, anticorps Orct, anticorps Orct1, anticorps Roct1, anticorps SLC22A2, anticorps solute carrier family 22 member 1, anticorps solute carrier family 22 (organic cation transporter), member 1, anticorps solute carrier family 22 member 2-like, anticorps SLC22A1, anticorps Slc22a1, anticorps LOC421584
    Sujet
    Synonyms:OCT1 Background:Translocates a broad array of organic cations with various structures and molecular weights including the model compounds 1-methyl-4-phenylpyridinium(MPP), tetraethylammonium(TEA), N-1-methylnicotinamide(NMN), 4-(4-(dimethylamino)styryl)-N-methylpyridinium(ASP), the endogenous compounds choline, guanidine, histamine, epinephrine, adrenaline, noradrenaline and dopamine, and the drugs quinine, and metformin. The transport of organic cations is inhibited by a broad array of compounds like tetramethylammonium(TMA), cocaine, lidocaine, NMDA receptor antagonists, atropine, prazosin, cimetidine, TEA and NMN, guanidine, cimetidine, choline, procainamide, quinine, tetrabutylammonium, and tetrapentylammonium. Translocates organic cations in an electrogenic and pH -independent manner. Translocates organic cations across the plasma membrane in both directions. Transports the polyamines spermine and spermidine. Transports pramipexole across the basolateral membrane of the proximal tubular epithelial cells. The choline transport is activated by MMTS. Regulated by various intracellular signaling pathways including inhibition by protein kinase A activation, and endogenously activation by the calmodulin complex, the calmodulin-dependent kinase II and LCK tyrosine kinase.
    Poids moléculaire
    61-67 kDa
    ID gène
    6580
    UniProt
    O15245
    Pathways
    Hormone Transport
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