SLC22A1 anticorps (AA 43-149)

N° du produit ABIN7170131

Détail du produit anti-SLC22A1 anticorps

Antigène: SLC22A1 (Solute Carrier Family 22 (Organic Cation Transporter), Member 1 (SLC22A1))

Épitope: AA 43-149

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SLC22A1 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Solute carrier family 22 member 1 protein (43-149AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur SLC22A1

Antigène: SLC22A1 (Solute Carrier Family 22 (Organic Cation Transporter), Member 1 (SLC22A1))

Autre désignation: SLC22A1 (SLC22A1 Produits)

Synonymes: anticorps SLC22A1, anticorps OCT1, anticorps HOCT1, anticorps oct1_cds, anticorps Lx1, anticorps Oct1, anticorps Orct, anticorps Orct1, anticorps Roct1, anticorps SLC22A2, anticorps solute carrier family 22 member 1, anticorps solute carrier family 22 (organic cation transporter), member 1, anticorps solute carrier family 22 member 2-like, anticorps SLC22A1, anticorps Slc22a1, anticorps LOC421584

Sujet:

Background: Translocates a broad array of organic cations with various structures and molecular weights including the model compounds 1-methyl-4-phenylpyridinium (MPP), tetraethylammonium (TEA), N-1-methylnicotinamide (NMN), 4-(4-(dimethylamino)styryl)-N-methylpyridinium (ASP), the endogenous compounds choline, guanidine, histamine, epinephrine, adrenaline, noradrenaline and dopamine, and the drugs quinine, and metformin. The transport of organic cations is inhibited by a broad array of compounds like tetramethylammonium (TMA), cocaine, lidocaine, NMDA receptor antagonists, atropine, prazosin, cimetidine, TEA and NMN, guanidine, cimetidine, choline, procainamide, quinine, tetrabutylammonium, and tetrapentylammonium. Translocates organic cations in an electrogenic and pH -independent manner. Translocates organic cations across the plasma membrane in both directions. Transports the polyamines spermine and spermidine. Transports pramipexole across the basolateral membrane of the proximal tubular epithelial cells. The choline transport is activated by MMTS. Regulated by various intracellular signaling pathways including inhibition by protein kinase A activation, and endogenously activation by the calmodulin complex, the calmodulin-dependent kinase II and LCK tyrosine kinase.

Aliases: hOCT1 antibody, OCT1 antibody, oct1_cds antibody, Organic cation transporter 1 antibody, S22A1_HUMAN antibody, Slc22a1 antibody, solute carrier family 22 (organic cation transporter), member 1 antibody, Solute carrier family 22 member 1 antibody

UniProt: O15245

Pathways: Hormone Transport