SLC22A1 anticorps

N° du produit ABIN969400

Détail du produit anti-SLC22A1 anticorps

Antigène: SLC22A1 (Solute Carrier Family 22 (Organic Cation Transporter), Member 1 (SLC22A1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp SLC22A1 est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Purification: purified

Immunogène: Purified recombinant fragment of human SLC22A1 expressed in E. coli.

Clone: 2C5

Isotype: IgG1

Information d'application

Indications d'application: ELISA: 1:10000, WB: 1:500 - 1:2000, FCM: 1:200 - 1:400

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: 4°C, -20°C for long term storage

Références pour anticorps anti-SLC22A1 (ABIN969400)

Zach, Krieger, Foedermayr, Zellhofer, Lutz: "OCT1 (SLC22A1) R61C polymorphism and response to imatinib treatment in chronic myeloid leukemia patients." dans: Leukemia & lymphoma, Vol. 49, Issue 11, pp. 2222-3, (2008) (PubMed).

Hirayama, Watanabe, Nakashima, Nanbu, Hamada, Kuniyasu, Nakayama, Kawaguchi, Saito: "Constitutive overexpression of P-glycoprotein, rather than breast cancer resistance protein or organic cation transporter 1, contributes to acquisition of imatinib-resistance in K562 cells." dans: Pharmaceutical research, Vol. 25, Issue 4, pp. 827-35, (2008) (PubMed).

Giannoudis, Davies, Lucas, Harris, Pirmohamed, Clark: "Effective dasatinib uptake may occur without human organic cation transporter 1 (hOCT1): implications for the treatment of imatinib-resistant chronic myeloid leukemia." dans: Blood, Vol. 112, Issue 8, pp. 3348-54, (2008) (PubMed).

Détails sur SLC22A1

Antigène: SLC22A1 (Solute Carrier Family 22 (Organic Cation Transporter), Member 1 (SLC22A1))

Autre désignation: SLC22A1 (SLC22A1 Produits)

Synonymes: anticorps SLC22A1, anticorps OCT1, anticorps HOCT1, anticorps oct1_cds, anticorps Lx1, anticorps Oct1, anticorps Orct, anticorps Orct1, anticorps Roct1, anticorps SLC22A2, anticorps solute carrier family 22 member 1, anticorps solute carrier family 22 (organic cation transporter), member 1, anticorps solute carrier family 22 member 2-like, anticorps SLC22A1, anticorps Slc22a1, anticorps LOC421584

Sujet:

Description: Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. This gene is one of three similar cation transporter genes located in a cluster on chromosome 6. The encoded protein contains twelve putative transmembrane domains and is a plasma integral membrane protein. Tissue specificity: Widely expressed with high level in liver.

Aliases: OCT1, HOCT1, oct1_cds, SLC22A1

Poids moléculaire: 61.2 kDa

ID gène: 6580

HGNC: 6580

Pathways: Hormone Transport