STIM1 anticorps

N° du produit ABIN7119553

Cet anticorps Souris Monoclonal détecte spécifiquement STIM1 dans WB, IHC et ELISA. Il présente une réactivité avec des échantillons de Humain, Rat et Souris.

Aperçu rapide pour STIM1 anticorps (ABIN7119553)

Antigène: STIM1 (Stromal Interaction Molecule 1 (STIM1))

Reactivité: Humain, Rat, Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp STIM1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Clone: 4G6

Détail du produit anti-STIM1 anticorps

Fonction: STIM1 antibody

Purification: Protein A+G purification

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: stromal interaction molecule 1

Isotype: IgG2a

Information d'application

Indications d'application: WB: 1:200-1:2000 IHC: 1:50-1:500

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur STIM1

Antigène: STIM1 (Stromal Interaction Molecule 1 (STIM1))

Autre désignation: STIM1

Sujet:

Synonyms: Stromal interaction molecule 1|STIM1|GOK

Background: Plays a role in mediating store-operated Ca(2+) entry(SOCE), a Ca(2+) influx following depletion of intracellular Ca(2+) stores(By similarity). Acts as Ca(2+) sensor in the endoplasmic reticulum via its EF-hand domain. Upon Ca(2+) depletion, translocates from the endoplasmic reticulum to the plasma membrane where it activates the Ca(2+) release-activated Ca(2+)(CRAC) channel subunit ORAI1(PubMed:16208375). Involved in enamel formation(By similarity). Activated following interaction with TMEM110/STIMATE, leading to promote STIM1 conformational switch(By similarity).

Poids moléculaire: 77 kDa

ID gène: 6786

UniProt: Q13586

Pathways: TCR Signaling, BCR Signaling