SNCA anticorps

N° du produit ABIN7119723

Cet anticorps anti-SNCA est un anticorps Souris Monoclonal détectant SNCA dans WB, ELISA et IHC. Adapté pour Humain, Souris et Rat.

Aperçu rapide pour SNCA anticorps (ABIN7119723)

Antigène: SNCA (Synuclein, alpha (SNCA))

Reactivité: Humain, Souris, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp SNCA est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Clone: 5C6

Détail du produit anti-SNCA anticorps

Fonction: SNCA antibody

Purification: protein A+G purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: synuclein, alpha (non A4 component of amyloid precursor)

Isotype: IgG1

Information d'application

Indications d'application: WB: 1:500 - 1:2000, IHC: 1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur SNCA

Antigène: SNCA (Synuclein, alpha (SNCA))

Autre désignation: SNCA

Sujet:

Synonyms: Alpha-synuclein|Non-A beta component of AD amyloid|Non-A4 component of amyloid precursor (NACP)|SNCA|NACP|PARK1

Background: Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Alternatively spliced transcripts encoding different isoforms have been identified for this gene.

Poids moléculaire: 18 kDa

ID gène: 6622

UniProt: P37840

Pathways: Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Platelet-derived growth Factor Receptor Signaling, Negative Regulation of Transporter Activity, Regulation of long-term Neuronal Synaptic Plasticity