VPS26B anticorps

N° du produit ABIN7120705

Cet anticorps Lapin Polyclonal détecte spécifiquement VPS26B dans ELISA et WB. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour VPS26B anticorps (ABIN7120705)

Antigène: VPS26B (Vacuolar Protein Sorting 26 Homolog B (VPS26B))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp VPS26B est non-conjugé

Application: ELISA, Western Blotting (WB)

Détail du produit anti-VPS26B anticorps

Fonction: VPS26B antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: vacuolar protein sorting 26 homolog B(S. pombe)

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:5000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur VPS26B

Antigène: VPS26B (Vacuolar Protein Sorting 26 Homolog B (VPS26B))

Autre désignation: VPS26B

Sujet:

Synonyms: Vacuolar protein sorting-associated protein 26B|Vesicle protein sorting 26B|VPS26B

Background: Acts as component of the retromer cargo-selective complex(CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway. The recruitment of the CSC to the endosomal membrane involves RAB7A and SNX3. The SNX-BAR retromer mediates retrograde transport of cargo proteins from endosomes to the trans-Golgi network(TGN) and is involved in endosome-to-plasma membrane transport for cargo protein recycling. The SNX3-retromer mediates the retrograde transport of WLS distinct from the SNX-BAR retromer pathway. The SNX27-retromer is believed to be involved in endosome-to-plasma membrane trafficking and recycling of a broad spectrum of cargo proteins. The CSC seems to act as recruitment hub for other proteins, such as the WASH complex and TBC1D5. May be involved in retrograde transport of SORT1 but not of IGF2R. Acts redundantly with VSP26A in SNX-27 mediated endocytic recycling of SLC2A1/GLUT1(By similarity).

Poids moléculaire: 39 kDa

ID gène: 112936

UniProt: Q4G0F5

Pathways: Cellular Glucan Metabolic Process