VPS26B anticorps (AA 1-336)

N° du produit ABIN7175296

Détail du produit anti-VPS26B anticorps

Antigène: VPS26B (Vacuolar Protein Sorting 26 Homolog B (VPS26B))

Épitope: AA 1-336

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp VPS26B est non-conjugé

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Réactivité croisée: Humain, Souris, Rat

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Vacuolar protein sorting-associated protein 26B protein (1-336AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur VPS26B

Antigène: VPS26B (Vacuolar Protein Sorting 26 Homolog B (VPS26B))

Autre désignation: VPS26B (VPS26B Produits)

Synonymes: anticorps VPS26B, anticorps wu:fb49d07, anticorps wu:fb50d06, anticorps zgc:56297, anticorps pep8b, anticorps vps26b, anticorps Pep8b, anticorps VP26B, anticorps 1810012I05Rik, anticorps 2310075A12Rik, anticorps AI848392, anticorps T29A15.180, anticorps T29A15_180, anticorps vacuolar protein sorting 26B, anticorps vacuolar protein sorting 26 homolog B (S. pombe), anticorps VPS26, retromer complex component B, anticorps VPS26 retromer complex component B, anticorps VPS26 retromer complex component B S homeolog, anticorps vacuolar protein sorting 26B, anticorps VPS26B, anticorps vps26b, anticorps vps26b.S, anticorps Vps26b

Sujet:

Background: Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway. The recruitment of the CSC to the endosomal membrane involves RAB7A and SNX3. The SNX-BAR retromer mediates retrograde transport of cargo proteins from endosomes to the trans-Golgi network (TGN) and is involved in endosome-to-plasma membrane transport for cargo protein recycling. The SNX3-retromer mediates the retrograde transport of WLS distinct from the SNX-BAR retromer pathway. The SNX27-retromer is believed to be involved in endosome-to-plasma membrane trafficking and recycling of a broad spectrum of cargo proteins. The CSC seems to act as recruitment hub for other proteins, such as the WASH complex and TBC1D5. May be involved in retrograde transport of SORT1 but not of IGF2R. Acts redundantly with VSP26A in SNX-27 mediated endocytic recycling of SLC2A1/GLUT1 (By similarity).

Aliases: Pep8b antibody, Vacuolar protein sorting 26 homolog B (S. pombe) antibody, Vacuolar protein sorting 26 homolog B (yeast) antibody, Vacuolar protein sorting-associated protein 26B antibody, Vesicle protein sorting 26B antibody, VP26B_HUMAN antibody, VPS26B antibody

UniProt: Q4G0F5

Pathways: Cellular Glucan Metabolic Process