VPS26B anticorps (Internal Region)
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- Antigène Voir toutes VPS26B Anticorps
- VPS26B (Vacuolar Protein Sorting 26 Homolog B (VPS26B))
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Épitope
- Internal Region
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Reactivité
- Humain, Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp VPS26B est non-conjugé
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Application
- ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)
- Specificité
- VPS26B Antibody detects endogenous levels of total VPS26B.
- Homologie
- Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogène
- A synthesized peptide derived from human VPS26B, corresponding to a region within the internal amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product VPS26B Anticorps primaire
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- Indications d'application
- WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20 °C. Stable for 12 months from date of receipt.
- Date de péremption
- 12 months
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- Antigène
- VPS26B (Vacuolar Protein Sorting 26 Homolog B (VPS26B))
- Autre désignation
- VPS26B (VPS26B Produits)
- Synonymes
- anticorps VPS26B, anticorps wu:fb49d07, anticorps wu:fb50d06, anticorps zgc:56297, anticorps pep8b, anticorps vps26b, anticorps Pep8b, anticorps VP26B, anticorps 1810012I05Rik, anticorps 2310075A12Rik, anticorps AI848392, anticorps T29A15.180, anticorps T29A15_180, anticorps vacuolar protein sorting 26B, anticorps vacuolar protein sorting 26 homolog B (S. pombe), anticorps VPS26, retromer complex component B, anticorps VPS26 retromer complex component B, anticorps VPS26 retromer complex component B S homeolog, anticorps vacuolar protein sorting 26B, anticorps VPS26B, anticorps vps26b, anticorps vps26b.S, anticorps Vps26b
- Sujet
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Description: Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway. The recruitment of the CSC to the endosomal membrane involves RAB7A and SNX3. The SNX-BAR retromer mediates retrograde transport of cargo proteins from endosomes to the trans-Golgi network (TGN) and is involved in endosome-to-plasma membrane transport for cargo protein recycling. The SNX3-retromer mediates the retrograde transport of WLS distinct from the SNX-BAR retromer pathway. The SNX27-retromer is believed to be involved in endosome-to-plasma membrane trafficking and recycling of a broad spectrum of cargo proteins. The CSC seems to act as recruitment hub for other proteins, such as the WASH complex and TBC1D5. May be involved in retrograde transport of SORT1 but not of IGF2R. Acts redundantly with VSP26A in SNX-27 mediated endocytic recycling of SLC2A1/GLUT1 (By similarity).
Gene: VPS26B
- Poids moléculaire
- 45 kDa
- ID gène
- 112936
- UniProt
- Q4G0F5
- Pathways
- Cellular Glucan Metabolic Process
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