Recombinant CD21 anticorps (C-Term)
Aperçu rapide pour Recombinant CD21 anticorps (C-Term) (ABIN7126254)
Antigène
Voir toutes CD21 (CR2) AnticorpsType d'anticorp
Reactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- C-Term
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Specificité
- CD21 also known as complement C3d receptor, Epstein-Barr virus receptor, and complement receptor type 2 (CR2), is a protein that in humans is encoded by the CR2 gene. This protein is involved in the complement system. It binds to iC3b (inactive derivative of C3b), C3dg, or C3d. B cells have CR2 receptors on their surfaces, allowing the complement system to play a role in B-cell activation and maturation.It is expressed by follicular dendritic cells (FDC) and mature B cells, as well as by several types of epithelial cells. CD21 is useful in the identification of follicular dendritic cell matrix found in normal lymph node and tonsillar tissue, and also useful in identifying abnormal.
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Réactivité croisée (Details)
- Human.
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Purification
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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Immunogène
- Synthetic peptide corresponding to CD21 residues within aa933-C terminal of CD21.
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Isotype
- IgG
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Indications d'application
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Known_Application: DilutionsImmunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.
Positive_Control: Human tonsil tissue.
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Restrictions
- For Research Use only
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Concentration
- 1.0 mg/mL
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Buffer
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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Agent conservateur
- Azide free
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Stock
- -20 °C,-80 °C
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Stockage commentaire
- Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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Date de péremption
- 24 months
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- CD21 (CR2) (Complement Component (3d/Epstein Barr Virus) Receptor 2 (CR2))
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Autre désignation
- CR2
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Sujet
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CD21, Complement C3d receptor (C3DR), Complement Receptor type 2 (CR2), CVID7, EBV receptor, EBV-R, Epstein-Barr virus receptor, EVBR, SLEB9,CD21 (Mature B-Cell & Follicular Dendritic Cell Marker)
Cellular localisation: Cell Surface -
Poids moléculaire
- 140kDa
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ID gène
- 1380, 445757
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UniProt
- P20023
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Pathways
- Système du Complément
Antigène
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