ELK1 anticorps

N° du produit ABIN7126329

L’anticorps Souris Monoclonal anti-ELK1 a été validé pour ELISA et IP. Il convient pour détecter ELK1 dans des échantillons de Humain.

Aperçu rapide pour ELK1 anticorps (ABIN7126329)

Antigène: ELK1 (ELK1, Member of ETS Oncogene Family (ELK1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp ELK1 est non-conjugé

Application: ELISA, Immunoprecipitation (IP)

Détail du produit anti-ELK1 anticorps

Specificité: Ets-1 is the prototype member of a family of genes identified on the basis of homology to the v-Ets oncogene isolated from the E26 erythroblastosis virus. This family of genes currently includes Ets-1, Ets-2, Erg-1 3, Elk-1, Elf-1, Elf-5, NERF, PU.1, PEA3, ERM, FEV, ER8l, Fli-1, TEL, Spi-B, ESE-1, ESE-3A, Net, ABT1and ERF. Members of the Ets gene family exhibit varied patterns of tissue expression, and share a highly conserved carboxy-terminal domain containing a sequence related to the SV40 large T antigen nuclear localization signal sequence. This conserved domain is essential for Ets-1 binding to DNA and is likely to be responsible for the DNA binding activity of all members of the Ets gene family. Several of these proteins have been shown to recognize similar motifs in DNA that share a centrally located 5'-GGAA-3' element.

Réactivité croisée (Details): Human.

Purification: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogène: Recombinant full-length human ELK1 protein

Isotype: IgG2a

Information d'application

Indications d'application:

Known_Application: ELISA, Immunoprecipitation (1-2 μg per 100-500 μg of total protein (1 mL of cell lysate)), ,Optimal dilution for a specific application should be determined.

Positive_Control: HeLa or K562 cells.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Date de péremption: 24 months

Détails sur ELK1

Antigène: ELK1 (ELK1, Member of ETS Oncogene Family (ELK1))

Autre désignation: ELK1

Sujet: ETS transcription factor, ELK2 member of ETS oncogene family, ETS domain-containing protein Elk-1, Member of ETS oncogene family, Tyrosine kinase (ELK1) oncogene,ELK1
Cellular localisation: Nucleus.

Poids moléculaire: 44.89kDa

ID gène: 2002, 181128

UniProt: P19419

Pathways: Signalisation MAPK, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades, Signaling of Hepatocyte Growth Factor Receptor, BCR Signaling